Raised alpha-fetoprotein levels in amniotic fluid and maternal serum associated with distension of the fetal bladder caused by absence of urethra.
نویسندگان
چکیده
Raised alpha-fetoprotein concentrations were found at 29 and 30 weeks' gestation in the amniotic fluid and maternal serum of a woman who presented in her seventh pregnancy with apparent polyhydramnios. The fetus had multiple abnormalities including gross distension of the bladder resulting from absence of the urethra, intestinal artresia, and a congenital heart defect.
منابع مشابه
The effects of electromagnetic fields on alpha-fetoprotein expression in the amniotic fluid of mouse embryo
Amniotic fluid (AF) is essential for fetal development and maturation during pregnancy. The levels of proteins in AF have been determined in many studies to screen for potential biomarkers of pregnancy-associated abnormalities. Alpha-fetoprotein (AFP) is a major AF and plasma protein produced by the yolk sac and the liver during the fetal period. APF serum concentrations are commonly used for s...
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عنوان ژورنال:
- Journal of medical genetics
دوره 15 1 شماره
صفحات -
تاریخ انتشار 1978